Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 10/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13028225 | 0.85 | HTR2A (0.54) | HTR2ASLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL2890163 | 0.85 | HTR2A (0.54) | HTR2ASLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL2892491 | 0.83 | HTR2A (0.58) | HTR2ASLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL13028234 | 0.81 | HTR2A (0.52) | HTR2ASLC6A4KCNH2L3MBTL1TDP1 | |
| SCHEMBL2890300 | 0.81 | HTR2A (0.52) | HTR2ASLC6A4KCNH2L3MBTL1TDP1 | |
| SCHEMBL2890310 | 0.80 | HTR2A (0.51) | HTR2ASLC6A4KCNH2L3MBTL1TDP1 | |
| SCHEMBL13028326 | 0.80 | HTR2A (0.51) | HTR2ASLC6A4KCNH2L3MBTL1TDP1 | |
| SCHEMBL2888447 | 0.79 | HTR2A (0.46) | HTR2ASLC6A4SLC6A2SLC6A3PPARA | |
| SCHEMBL13028226 | 0.79 | HTR2A (0.46) | HTR2ASLC6A4SLC6A2SLC6A3PPARA | |
| SCHEMBL12929642 | 0.76 | SLC6A4 (0.68) | HTR2ASLC6A4SLC6A2SLC6A3PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8558028-B2 | Compound capable of inhibiting 17-beta hydroxysteriod dehydrogenase | UNIVERSITY OF BATH OF CLAVERTON DOWN (GB) | 2013-10-15 | — | — | US | disclosed |
| US-20100286204-A1 | COMPOUND CAPABLE OF INHIBITING 17-BETA HYDROXYSTERIOD DEHYDROGENASE | STERIX LIMITED (GB) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286204-A1 | COMPOUND CAPABLE OF INHIBITING 17-BETA HYDROXYSTERIOD DEHYDROGENASE | HSD17B13, HSD17B3, HSD3B2 | HTR2A 1938/4885SLC6A4 1489/4885SLC6A2 1925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.