Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 18/20 | 0.40 |
| ▸ | BUB1 | O43683 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16123282 | 0.85 | BUB1 (0.45) | MAPKAPK2BUB1 | |
| SCHEMBL31529824 | 0.85 | BUB1 (0.45) | MAPKAPK2BUB1 | |
| SCHEMBL28369828 | 0.81 | MAPKAPK2 (0.38) | MAPKAPK2BUB1 | |
| SCHEMBL3579503 | 0.75 | MAPKAPK2 (0.66) | MAPKAPK2 | |
| SCHEMBL1908915 | 0.72 | MAPKAPK2 (0.67) | MAPKAPK2BUB1 | |
| SCHEMBL1908925 | 0.71 | MAPKAPK2 (0.38) | MAPKAPK2 | |
| SCHEMBL1909058 | 0.70 | MAPKAPK2 (0.40) | MAPKAPK2BUB1 | |
| SCHEMBL1908920 | 0.70 | MAPKAPK2 (0.62) | MAPKAPK2BUB1 | |
| SCHEMBL17847539 | 0.70 | BUB1 (0.43) | MAPKAPK2BUB1 | |
| SCHEMBL1908916 | 0.69 | MAPKAPK2 (0.56) | MAPKAPK2BUB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110746424-A | MK2 inhibitors and uses thereof | 西建卡尔有限责任公司 | 2020-02-04 | — | — | CN | disclosed |