Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 known ✓ | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 known ✓ | Q92769 | 2/20 | 0.39 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.39 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.39 |
| ▸ | HRH1 known ✓ | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 known ✓ | P35462 | 1/20 | 0.39 |
| ▸ | HDAC3 known ✓ | O15379 | 1/20 | 0.38 |
| ▸ | HDAC8 known ✓ | Q9BY41 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL28371979 | 1.00 | TP53 (0.69) | TP53FFAR3CYP1A2SMN1; SMN2HDAC1 | |
| Lactic Acid SCHEMBL11064545 | 0.94 | TP53 (0.61) | TP53FFAR3CYP1A2SMN1; SMN2HDAC1 | |
| Lactic Acid SCHEMBL28965389 | 0.92 | TP53 (0.58) | TP53FFAR3CYP1A2SMN1; SMN2HDAC1 | |
| Lactic Acid SCHEMBL8734273 | 0.89 | TP53 (0.55) | TP53FFAR3CYP1A2SMN1; SMN2HDAC1 | |
| Lactic Acid SCHEMBL27721040 | 0.87 | — | — | |
| Propionic Acid SCHEMBL27791535 | 0.87 | — | — | |
| Propionic Acid SCHEMBL1237963 | 0.84 | FFAR3 (0.67) | TP53FFAR3CYP1A2HDAC1HDAC2 | |
| Propionic Acid SCHEMBL11428745 | 0.84 | FFAR3 (0.67) | TP53FFAR3CYP1A2HDAC1HDAC2 | |
| Lactic Acid SCHEMBL3928098 | 0.84 | — | — | |
| Propionic Acid SCHEMBL27910383 | 0.84 | FFAR3 (0.67) | TP53FFAR3CYP1A2SMN1; SMN2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115745946-B | Low-temperature preparation method of glycolide and lactide | 中国科学院长春应用化学研究所 | 2024-03-26 | — | — | CN | claimed |
| CN-115650948-B | Preparation method of glycolide-lactide | 中国科学院长春应用化学研究所 | 2023-12-19 | — | — | CN | claimed |
| CN-115745946-A | Low-temperature preparation method of glycolide-lactide | 中国科学院长春应用化学研究所 | 2023-03-07 | — | — | CN | claimed |
| CN-115650948-A | Preparation method of glycolide-lactide | 中国科学院长春应用化学研究所 | 2023-01-31 | — | — | CN | claimed |
| EP-1691621-B1 | DAIRY PRODUCT AND PROCESS | FONTERRA CO OPERATIVE GROUP (NZ) | 2013-10-23 | — | — | EP | claimed |
| WO-2011068403-A2 | NOVEL N-{3-ETHYNYLPHENYLAMINO)-6,7-BIS(2-METHOXYETHOXY)-4-QUINAZOLINAMJNE SALTS | ULTIMORPHIX TECHNOLOGIES B.V. (NL) | 2011-06-09 | — | — | WO | claimed |
| CN-101933562-A | Premix forfermented total mixed rations (TMR) for dairy cows and preparation process thereof | INST OF SHANGHAI DAIRY SCIENCE | 2011-01-05 | — | — | CN | claimed |
| EP-1691621-A2 | DAIRY PRODUCT AND PROCESS | Elston, Peter Dudley (NZ) | 2006-08-23 | — | — | EP | claimed |
| WO-2005046344-A2 | DAIRY PRODUCT AND PROCESS | ELSTON PETER DUDLEY (NZ) | 2005-05-26 | — | — | WO | claimed |
| CN-115745946-B | Low-temperature preparation method of glycolide and lactide | 中国科学院长春应用化学研究所 | 2024-03-26 | — | — | CN | disclosed |
| EP-4292828-A1 | UNPRINTED INKJET-PRINTABLE FILLABLE POUCHES AND METHODS FOR PRODUCING AND PRINTING SAID POUCHES | Sihl GmbH (DE) | 2023-12-20 | — | — | EP | disclosed |
| CN-115650948-B | Preparation method of glycolide-lactide | 中国科学院长春应用化学研究所 | 2023-12-19 | — | — | CN | disclosed |
| US-20230399158-A1 | Unprinted Inkjet-Printable Fillable Pouches and Methods for Producing and Printing Said Pouches | SIHL GMBH (DE) | 2023-12-14 | — | — | US | disclosed |
| CN-115745946-A | Low-temperature preparation method of glycolide-lactide | 中国科学院长春应用化学研究所 | 2023-03-07 | — | — | CN | disclosed |
| CN-1367653-A | Mixing triglyceride containing medium-chain fatty acid and exogenous lipolytic enzyme as feed additive | AVEVE NV (BE) | 2002-09-04 | — | — | CN | disclosed |
| WO-1989006662-A1 | MODIFIED ADVANCED EPOXY RESINS | THE DOW CHEMICAL COMPANY (US) | 1989-07-27 | — | — | WO | disclosed |
| EP-0324405-A2 | Modified advanced epoxy resins | THE DOW CHEMICAL COMPANY (US) | 1989-07-19 | — | — | EP | disclosed |
| US-4835225-A | Modified advanced epoxy resins | THE DOW CHEMICAL COMPANY (US) | 1989-05-30 | — | — | US | disclosed |
| US-4508737-A | CONTROLLING FERM,ENTATION BY ADDING ALKALI SULFITE, BUSULFITE OR METABISULFITE | INTERNATIONAL STOCK FOOD CORPORATION (US) | 1985-04-02 | — | — | US | disclosed |
| US-4260452-A | DEPITHING, PULPING | KRUEGER HORST | 1981-04-07 | — | — | US | disclosed |