SCHEMBL2888979

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12975642	0.89	GRM1 (0.56)	GRM1GRM5HRH1TMEM97TRPV1
	SCHEMBL12975637	0.87	GRM1 (0.76)	GRM1GRM5HRH1TMEM97TRPV1
	SCHEMBL2890559	0.87	GRM1 (0.78)	GRM1GRM5HRH1TMEM97TRPV1
	SCHEMBL2889701	0.86	GRM1 (0.69)	GRM1GRM5HRH1TMEM97TRPV1
	SCHEMBL2889095	0.86	GRM1 (0.68)	GRM1GRM5HRH1TMEM97TRPV1
	SCHEMBL2891637	0.85	GRM1 (0.77)	GRM1GRM5HRH1TMEM97
	SCHEMBL2892619	0.85	GRM1 (0.72)	GRM1GRM5HRH1TMEM97TRPV1
	SCHEMBL12975649	0.84	GRM1 (0.74)	GRM1GRM5HRH1TMEM97TRPV1
	SCHEMBL12975656	0.83	GRM1 (0.73)	GRM1GRM5HRH1TMEM97TRPV1
	SCHEMBL658737	0.83	GRM1 (1.00)	GRM1GRM5HRH1TMEM97TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.