Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 16/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28889827 | 0.78 | PTPN11 (0.36) | PTPN11ADORA2AADORA1 | |
| SCHEMBL29284616 | 0.77 | ACACB (0.33) | PTPN11ACACBADORA2AADORA1 | |
| SCHEMBL29021059 | 0.73 | PTPN11 (0.31) | PTPN11 | |
| SCHEMBL26920421 | 0.72 | PTPN11 (0.35) | PTPN11ADORA2AADORA1 | |
| SCHEMBL21631725 | 0.72 | ADORA2A (0.38) | PTPN11ADORA2AADORA1 | |
| SCHEMBL23508730 | 0.72 | PTPN11 (0.37) | PTPN11ADORA2AADORA1 | |
| SCHEMBL21631652 | 0.70 | PTPN11 (0.36) | PTPN11ADORA2AADORA1 | |
| SCHEMBL21653696 | 0.70 | ADORA2A (0.42) | PTPN11ADORA2AADORA1ADORA3 | |
| SCHEMBL24879337 | 0.70 | PTPN11 (0.36) | PTPN11ADORA2AADORA1 | |
| SCHEMBL26156073 | 0.70 | PTPN11 (0.36) | PTPN11ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115340545-A | Bicyclic heteroaryl derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2022-11-15 | — | — | CN | disclosed |