SCHEMBL28889986

SCHEMBL28889986

CCCCCON=C1CCCCC1

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.35
FAAH O00519 1/20 0.35
ABHD16A O95870 1/20 0.35
KMT2A Q03164 1/20 0.35
PLA2G7 Q13093 1/20 0.35
NCEH1 Q6PIU2 1/20 0.35
DAGLB Q8NCG7 1/20 0.35
DAGLA Q9Y4D2 1/20 0.35
ESR1 P03372 1/20 0.33
TSHR P16473 2/20 0.31
LTA4H P09960 1/20 0.31
CASP1 P29466 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11327111 0.98 MEN1 (0.38) MEN1FAAHABHD16AKMT2APLA2G7
SCHEMBL13488624 0.94 ESR1 (0.37) MEN1FAAHABHD16AKMT2APLA2G7
SCHEMBL7540680 0.85 CHRM2 (0.36) MEN1FAAHABHD16AKMT2APLA2G7
SCHEMBL22050100 0.81 ESR1 (0.31) ESR1
SCHEMBL11370781 0.78 HRH3 (0.41)
SCHEMBL11383062 0.77 HRH3 (0.39) MEN1FAAHABHD16AKMT2APLA2G7
SCHEMBL10962373 0.77 HRH3 (0.39) MEN1FAAHABHD16AKMT2APLA2G7
SCHEMBL7541983 0.76 KMT2A (0.36) MEN1FAAHABHD16AKMT2APLA2G7
SCHEMBL12465180 0.73
SCHEMBL11381061 0.73 HRH3 (0.38) MEN1KMT2ATSHRLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111138325-A Preparation method of (Z) - β -sulfonyl enamine compound 台州学院 2020-05-12 CN claimed