Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ESRRG | P62508 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21148968 | 1.00 | MEN1 (0.41) | MEN1KMT2APTPN1ADRB3ADRB2 | |
| SCHEMBL20907565 | 0.87 | KMT2A (0.40) | MEN1KMT2APTPN1ADRB3NPC1 | |
| SCHEMBL20908058 | 0.87 | KMT2A (0.40) | MEN1KMT2APTPN1ADRB3NPC1 | |
| SCHEMBL21149522 | 0.87 | PTPN1 (0.41) | MEN1KMT2APTPN1LMNANPSR1 | |
| SCHEMBL20907878 | 0.87 | PTPN1 (0.41) | MEN1KMT2APTPN1LMNANPSR1 | |
| SCHEMBL20907868 | 0.83 | EPHX2 (0.38) | MEN1KMT2APTPN1ADRB3ADRB2 | |
| SCHEMBL21150257 | 0.83 | MEN1 (0.38) | MEN1KMT2APTPN1ADRB3SMN1; SMN2 | |
| SCHEMBL20907601 | 0.83 | MEN1 (0.38) | MEN1KMT2APTPN1ADRB3SMN1; SMN2 | |
| SCHEMBL28889780 | 0.83 | EPHX2 (0.38) | MEN1KMT2APTPN1ADRB3ADRB2 | |
| SCHEMBL20908060 | 0.80 | FFAR4 (0.36) | MEN1KMT2AADRB2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111212832-B | 1-Benzyl-2-imino-4-phenyl-5-oxoimidazolidine derivatives as HIV protease inhibitors | 吉利德科学公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-111212832-A | 1-benzyl-2-imino-4-phenyl-5-oxoimidazolidine derivatives as HIV protease inhibitors | 吉利德科学公司 | 2020-05-29 | — | — | CN | disclosed |