Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 17/20 | 0.68 |
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.63 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29958269 | 1.00 | TLR8 (0.68) | TLR8TLR7PRMT5IDO1KCNH2 | |
| SCHEMBL28959300 | 1.00 | TLR8 (0.68) | TLR8TLR7PRMT5IDO1KCNH2 | |
| SCHEMBL29956995 | 1.00 | TLR8 (0.68) | TLR8TLR7PRMT5IDO1KCNH2 | |
| SCHEMBL29957549 | 1.00 | TLR8 (0.68) | TLR8TLR7PRMT5IDO1KCNH2 | |
| SCHEMBL28890540 | 1.00 | TLR8 (0.68) | TLR8TLR7PRMT5IDO1KCNH2 | |
| SCHEMBL28890448 | 0.97 | TLR8 (0.67) | TLR8TLR7PRMT5IDO1KCNH2 | |
| SCHEMBL30949795 | 0.97 | TLR8 (0.67) | TLR8TLR7PRMT5IDO1KCNH2 | |
| SCHEMBL28890492 | 0.97 | TLR8 (0.67) | TLR8TLR7PRMT5IDO1KCNH2 | |
| SCHEMBL30949800 | 0.97 | TLR8 (0.67) | TLR8TLR7PRMT5IDO1KCNH2 | |
| SCHEMBL29236195 | 0.97 | TLR8 (0.67) | TLR8TLR7PRMT5IDO1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115362155-B | Arylamine derivative, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-115362155-A | Arylamine derivatives, and preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2022-11-18 | — | — | CN | disclosed |