Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 4/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Stearic Acid SCHEMBL28405672 | 0.91 | CYP1A2 (0.54) | ALDH1A1CES1 | |
| Myristic Acid SCHEMBL28405674 | 0.91 | CYP1A2 (0.54) | ALDH1A1CES1 | |
| Palmitic Acid SCHEMBL28405218 | 0.91 | CYP1A2 (0.54) | ALDH1A1CES1 | |
| Succinic Acid SCHEMBL28410783 | 0.88 | FFAR1 (0.50) | FFAR1CYP2A6SMN1; SMN2ALDH1A1CES1 | |
| Propionic Acid SCHEMBL28890107 | 0.84 | CYP2A6 (0.52) | FFAR1CYP2A6ALDH1A1L3MBTL1DHODH | |
| SCHEMBL5309049 | 0.81 | FFAR1 (0.64) | FFAR1CES1 | |
| Acetone SCHEMBL28141566 | 0.81 | CYP2A6 (0.57) | CYP2A6ALDH1A1L3MBTL1DHODH | |
| SCHEMBL28214265 | 0.81 | CYP2A6 (0.57) | CYP2A6SMN1; SMN2ALDH1A1L3MBTL1DHODH | |
| Benzene SCHEMBL29224585 | 0.80 | KDM4E (0.68) | CYP2A6SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL35754 | 0.80 | KDM4E (0.68) | CYP2A6SMN1; SMN2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111097050-A | Composition comprising fatty acid or derivative thereof and phenylpyridine derivative | 黄泳华 | 2020-05-05 | — | — | CN | disclosed |