SCHEMBL28890682

SCHEMBL28890682

O=Cc1ccc(Nc2ccc(-c3ccc(C=O)s3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.48
CYP2E1 P05181 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2A6 P11509 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2B6 P20813 1/20 0.45
CYP2C19 P33261 1/20 0.45
MAPT P10636 2/20 0.41
PRF1 P14222 3/20 0.40
DPP4 P27487 1/20 0.40
PGR P06401 1/20 0.37
CHRM2 P08172 1/20 0.36
CHRM4 P08173 1/20 0.36
CHRM5 P08912 1/20 0.36
CHRM1 P11229 1/20 0.36
CHRM3 P20309 1/20 0.36
CYP11B1 P15538 1/20 0.35
CYP11B2 P19099 1/20 0.35
GAA P10253 2/20 0.33
KDM4E B2RXH2 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32679340 0.85 APP (0.47) APPCYP2E1CYP3A4CYP2A6CYP2C9
SCHEMBL28403012 0.82 EGFR (0.49) APPCYP2E1CYP3A4CYP2A6CYP2C9
SCHEMBL29898511 0.80 APP (0.72) APPCYP2E1CYP3A4CYP2A6CYP2C9
SCHEMBL9131202 0.78 DRD1 (0.45) CYP2A6GAAKDM4EALDH1A1
SCHEMBL16334779 0.76 APP (0.48) APPCYP2E1CYP3A4CYP2A6CYP2C9
SCHEMBL4444483 0.76 APP (0.47) APPCYP2A6MAPTDPP4ALDH1A1
SCHEMBL7554959 0.75 CYP2A6 (0.50) CYP2A6GAAKDM4EALDH1A1
SCHEMBL2017152 0.74 PRF1 (0.58) APPCYP2E1CYP3A4CYP2A6CYP2C9
SCHEMBL28402564 0.73 HDAC2 (0.51) DPP4CYP11B1CYP11B2
SCHEMBL1133750 0.73 APP (0.54) APPCYP2E1CYP3A4CYP2A6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111233824-B Organic spectrum conversion material, preparation method thereof and luminescent solar concentrator comprising organic spectrum conversion material 紫石能源有限公司 2022-09-09 CN disclosed
CN-111233824-A Organic spectrum conversion material, preparation method thereof and luminescent solar concentrator comprising organic spectrum conversion material 东泰高科装备科技有限公司 2020-06-05 CN disclosed