⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15651255 | 1.00 | TSHR (0.43) | — | |
| SCHEMBL50175 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL929894 | 0.96 | — | — | |
| Ammonia Solution, Strong SCHEMBL9543083 | 0.96 | — | — | |
| Bromide SCHEMBL8067104 | 0.96 | — | — | |
| Propane SCHEMBL27421619 | 0.96 | — | — | |
| Bromide SCHEMBL15916956 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL22437570 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL28828349 | 0.93 | — | — | |
| Water SCHEMBL7740655 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116854630-B | Methods and intermediates for preparing therapeutic compounds useful in the treatment of retroviral infections | 吉利德科学公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-116854630-A | Methods and intermediates for preparing therapeutic compounds useful in the treatment of retroviral infections | 吉利德科学公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-112055712-B | Methods and intermediates for preparing therapeutic compounds useful in the treatment of retroviral infections | 吉利德科学公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-110628739-B | Amine dehydrogenase mutant and application thereof in synthesis of chiral amine and amino alcohol | 华东理工大学 | 2021-04-09 | — | — | CN | disclosed |
| EP-2427456-B1 | ISOXAZOLE-PYRIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2020-02-05 | — | — | EP | disclosed |
| CN-110628739-A | Amine dehydrogenase mutant and application thereof in synthesis of chiral amine and amino alcohol | 华东理工大学 | 2019-12-31 | — | — | CN | disclosed |
| US-8415379-B2 | Pyridines | HOFFMANN-LA ROCHE INC. (US) | 2013-04-09 | — | — | US | disclosed |
| US-20100286132-A1 | PYRIDINES | ROCHE PALO ALTO LLC | 2010-11-11 | — | — | US | disclosed |
| WO-2010127976-A1 | ISOXAZOLE-PYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2010-11-11 | — | — | WO | disclosed |