Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 9/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28890959 | 1.00 | PDE5A (0.85) | PDE5A | |
| SCHEMBL8499754 | 0.95 | PDE5A (0.89) | PDE5A | |
| SCHEMBL8486537 | 0.92 | PDE5A (0.83) | PDE5A | |
| SCHEMBL28412519 | 0.92 | PDE5A (0.83) | PDE5A | |
| SCHEMBL20832907 | 0.92 | PDE5A (0.85) | PDE5A | |
| SCHEMBL28415169 | 0.92 | PDE5A (0.81) | PDE5A | |
| SCHEMBL28415166 | 0.92 | PDE5A (0.81) | PDE5A | |
| SCHEMBL8487823 | 0.92 | PDE5A (0.81) | PDE5A | |
| Avanafil SCHEMBL118799 | 0.91 | PDE5A (1.00) | PDE5A | |
| Avanafil SCHEMBL16377474 | 0.91 | PDE5A (1.00) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111297868-A | Use of a composition comprising a heterocyclic compound for the manufacture of a medicament for the treatment of phosphodiesterase mediated diseases | 黄泳华 | 2020-06-19 | — | — | CN | claimed |
| CN-111297868-A | Use of a composition comprising a heterocyclic compound for the manufacture of a medicament for the treatment of phosphodiesterase mediated diseases | 黄泳华 | 2020-06-19 | — | — | CN | disclosed |