SCHEMBL28891740

SCHEMBL28891740

O=C(C(F)(F)F)C(F)(F)F.c1ccc(P(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
ESR1 P03372 2/20 0.48
ESR2 Q92731 2/20 0.48
CES1 P23141 7/20 0.46
PTPN1 P18031 1/20 0.35
FAAH O00519 3/20 0.35
HDAC6 Q9UBN7 2/20 0.35
CES2 O00748 1/20 0.34
CA2 P00918 1/20 0.34
CA4 P22748 1/20 0.34
KDM4E B2RXH2 1/20 0.34
GAA P10253 1/20 0.34
CPA1 P15085 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL8364947 0.88 CYP3A4 (0.57) CYP3A4TDP1ESR1ESR2CES1
Trifluoroacetic Acid SCHEMBL27963324 0.88 CYP3A4 (0.57) CYP3A4TDP1ESR1ESR2CES1
Trifluoroacetic Acid SCHEMBL27870901 0.86 CYP3A4 (0.55) CYP3A4TDP1ESR1ESR2CES1
Trifluoroacetic Acid SCHEMBL31532238 0.86 CYP3A4 (0.55) CYP3A4TDP1ESR1ESR2CES1
Trifluoroacetic Acid SCHEMBL27511572 0.86 CYP3A4 (0.55) CYP3A4TDP1ESR1ESR2CES1
Trifluoroacetic Acid SCHEMBL30195537 0.86 CYP3A4 (0.55) CYP3A4TDP1ESR1ESR2CES1
Trifluoroacetic Acid SCHEMBL11783673 0.86 CYP3A4 (0.55) CYP3A4TDP1ESR1ESR2CES1
Trifluoroacetic Acid SCHEMBL18425261 0.86 CYP3A4 (0.55) CYP3A4TDP1ESR1ESR2CES1
Trifluoroacetic Acid SCHEMBL27516099 0.86 CYP3A4 (0.55) CYP3A4TDP1ESR1ESR2CES1
Trifluoroacetic Acid SCHEMBL7593901 0.84 TDP1 (0.52) CYP3A4TDP1ESR1ESR2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115197432-B Antibacterial/antiviral polymer material and preparation method thereof 中国科学院长春应用化学研究所 2024-03-26 CN disclosed
CN-115197432-A Antibacterial/antiviral high polymer material and preparation method thereof 中国科学院长春应用化学研究所 2022-10-18 CN disclosed