Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 8/20 | 0.63 |
| ▸ | GSK3A | P49840 | 4/20 | 0.61 |
| ▸ | PRKCA | P17252 | 2/20 | 0.57 |
| ▸ | RGS4 | P49798 | 7/20 | 0.53 |
| ▸ | RGS8 | P57771 | 7/20 | 0.53 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.52 |
| ▸ | CDK1 | P06493 | 1/20 | 0.52 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.52 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28891819 | 0.93 | GSK3B (0.60) | GSK3BGSK3APRKCARGS4RGS8 | |
| SCHEMBL26420836 | 0.87 | GSK3B (0.66) | GSK3BGSK3APRKCARGS4RGS8 | |
| SCHEMBL26420835 | 0.86 | GSK3B (0.64) | GSK3BGSK3APRKCARGS4RGS8 | |
| SCHEMBL28891688 | 0.85 | GSK3B (0.68) | GSK3BGSK3APRKCARGS4RGS8 | |
| Hydrochloric Acid SCHEMBL28891664 | 0.82 | GSK3B (0.60) | GSK3BGSK3APRKCARGS4RGS8 | |
| SCHEMBL29039825 | 0.82 | GSK3B (0.60) | GSK3BGSK3APRKCARGS4RGS8 | |
| SCHEMBL28891886 | 0.81 | GSK3B (0.59) | GSK3BGSK3APRKCARGS4RGS8 | |
| SCHEMBL29039817 | 0.81 | GSK3B (0.57) | GSK3BGSK3APRKCARGS4RGS8 | |
| SCHEMBL28891760 | 0.80 | GSK3B (0.60) | GSK3BGSK3APRKCARGS4RGS8 | |
| Hydrochloric Acid SCHEMBL28891883 | 0.80 | GSK3B (0.60) | GSK3BGSK3APRKCARGS4RGS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116675653-B | Aminoalkyl substituted 1,2, 4-thiadiazolidine-3, 5-dione compound, preparation method and application thereof | 中国药科大学 | 2024-10-01 | — | — | CN | disclosed |
| CN-116675653-A | Aminoalkyl substituted 1,2, 4-thiadiazolidine-3, 5-dione compound, preparation method and application thereof | 中国药科大学 | 2023-09-01 | — | — | CN | disclosed |
| CN-115197167-B | 1,2, 4-thiadiazolidine-3, 5-dione compound, and preparation method and application thereof | 中国药科大学 | 2023-07-28 | — | — | CN | disclosed |
| CN-115197167-A | 1,2,4-thiadiazolidine-3,5-diketone compound and preparation method and application thereof | 中国药科大学 | 2022-10-18 | — | — | CN | disclosed |