SCHEMBL2889357

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2890478	0.87	GRM1 (0.71)	GRM1GRM5PTGS1PTGS2DDX3X
	SCHEMBL2892824	0.84	GRM1 (1.00)	GRM1GRM5ENPP2
	SCHEMBL2891168	0.82	GRM1 (0.72)	GRM1GRM5PTGS1PTGS2
	SCHEMBL8614176	0.73	GRM1 (1.00)	GRM1GRM5
	SCHEMBL2889303	0.73	GRM1 (0.74)	GRM1GRM5
	SCHEMBL2893810	0.73	GRM1 (1.00)	GRM1GRM5
	SCHEMBL2891855	0.73	GRM1 (1.00)	GRM1GRM5
	SCHEMBL2888969	0.72	GRM1 (0.72)	GRM1GRM5
	SCHEMBL27007743	0.71	GRM1 (0.78)	GRM1GRM5ENPP2
	SCHEMBL2893490	0.71	GRM1 (0.62)	GRM1GRM5FAAHMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.