Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 4/20 | 0.48 |
| ▸ | PIM1 | P11309 | 3/20 | 0.48 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.48 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.48 |
| ▸ | PAK4 | O96013 | 1/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.48 |
| ▸ | PRKCG | P05129 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | FES | P07332 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30085671 | 1.00 | CDC7 (0.48) | CDC7PIM1PIM2DYRK1ACLK4 | |
| SCHEMBL30085793 | 1.00 | CDC7 (0.48) | CDC7PIM1PIM2DYRK1ACLK4 | |
| SCHEMBL28895048 | 1.00 | CDC7 (0.48) | CDC7PIM1PIM2DYRK1ACLK4 | |
| SCHEMBL28895052 | 1.00 | CDC7 (0.48) | CDC7PIM1PIM2DYRK1ACLK4 | |
| SCHEMBL28894894 | 0.90 | GBA1 (0.51) | CDC7DYRK1ACLK4CHEK1MAPK13 | |
| SCHEMBL30085846 | 0.90 | GBA1 (0.51) | CDC7DYRK1ACLK4CHEK1MAPK13 | |
| SCHEMBL28895196 | 0.89 | PIM1 (0.45) | PIM1DYRK1ACLK4GBA1PPARG | |
| SCHEMBL28895197 | 0.89 | PIM1 (0.45) | PIM1DYRK1ACLK4GBA1PPARG | |
| SCHEMBL30085464 | 0.89 | PIM1 (0.45) | PIM1DYRK1ACLK4GBA1PPARG | |
| SCHEMBL28894682 | 0.87 | IKBKB (0.51) | PIM1DYRK1ACLK4CHEK1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115397818-A | Aminopyrimidine derivatives and their use as modulators of arene receptors | 东亚ST株式会社 | 2022-11-25 | — | — | CN | claimed |