Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 20/20 | 0.62 |
| ▸ | DYRK1A | Q13627 | 20/20 | 0.62 |
| ▸ | WNT1 | P04628 | 5/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28895388 | 0.83 | DYRK1A (0.60) | GSK3BDYRK1AWNT1 | |
| SCHEMBL28895176 | 0.83 | GSK3B (0.54) | GSK3BDYRK1AWNT1 | |
| SCHEMBL28895359 | 0.82 | GSK3B (0.69) | GSK3BDYRK1AWNT1 | |
| SCHEMBL19516224 | 0.82 | GSK3B (0.69) | GSK3BDYRK1AWNT1 | |
| SCHEMBL28895452 | 0.82 | GSK3B (0.63) | GSK3BDYRK1AWNT1 | |
| SCHEMBL28959765 | 0.81 | GSK3B (0.65) | GSK3BDYRK1AWNT1 | |
| SCHEMBL28895316 | 0.80 | GSK3B (0.73) | GSK3BDYRK1AWNT1 | |
| SCHEMBL19518447 | 0.78 | GSK3B (0.86) | GSK3BDYRK1AWNT1 | |
| SCHEMBL19515312 | 0.77 | GSK3B (0.74) | GSK3BDYRK1AWNT1 | |
| SCHEMBL19515311 | 0.77 | GSK3B (0.74) | GSK3BDYRK1AWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311819-B | Isoquinolin-3-yl carboxamides, their preparation and their use | 萨穆梅德有限公司 | 2022-10-25 | — | — | CN | claimed |