SCHEMBL28895635

SCHEMBL28895635

FC(F)[CH]CC(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1992500 0.72
SCHEMBL15061158 0.70
SCHEMBL1990839 0.67
SCHEMBL30367005 0.67
SCHEMBL2051931 0.65
SCHEMBL2495482 0.64
SCHEMBL610481 0.64
SCHEMBL1993707 0.64
SCHEMBL15661694 0.61
SCHEMBL722777 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114127073-B Imidazopyrimidines as EED inhibitors and use thereof 密歇根大学董事会 2024-05-31 CN disclosed
CN-117897382-A Nitrogen-containing tricyclic compounds and pharmaceutical uses thereof 日本烟草产业株式会社 2024-04-16 CN disclosed
CN-117813098-A Methods of treating diseases or conditions 苏州亚盛药业有限公司 2024-04-02 CN disclosed
CN-117794930-A KRAS inhibitors 苏州亚盛药业有限公司 2024-03-29 CN disclosed
CN-117616032-A Rare earth complex 东曹株式会社 2024-02-27 CN disclosed
CN-116916963-A Multivalent ligand clusters with diamine scaffolds for targeted delivery of therapeutic agents 上海舶望制药有限公司 2023-10-20 CN disclosed
CN-112300130-B Tricyclic compounds as BCR-ABL inhibitors 苏州亚盛药业有限公司 2023-04-25 CN disclosed
CN-113087700-B Spirocyclic tetrahydroquinazolines 苏州亚盛药业有限公司 2023-03-14 CN disclosed
CN-115380033-A SETD2 inhibitors and related methods and uses, including combination therapies EPIZYME股份有限公司 2022-11-22 CN disclosed
CN-115212311-A Pharmaceutical composition and application thereof 苏州亚盛药业有限公司 2022-10-21 CN disclosed