Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CTH | P32929 | 1/20 | 0.31 |
| ▸ | CBS | P35520 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28898044 | 1.00 | GRIK1 (0.33) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL28710900 | 0.76 | GRIK1 (0.32) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL28697890 | 0.76 | GRIK1 (0.32) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL28697891 | 0.76 | GRIK1 (0.32) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL26084660 | 0.76 | CYP2D6 (0.33) | — | |
| SCHEMBL22315709 | 0.76 | CYP2D6 (0.33) | — | |
| SCHEMBL16648891 | 0.75 | GRIK1 (0.33) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7646402 | 0.74 | — | — | |
| SCHEMBL6642937 | 0.74 | — | — | |
| SCHEMBL28440516 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111518101-B | Pyrrolopyrimidine derivatives and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-113999236-A | Salt of nitrogen-containing heterocyclic compound and solid form, pharmaceutical composition and application of salt | 武汉人福创新药物研发中心有限公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-113999235-A | Solid forms of nitrogen-containing heterocyclic compounds, pharmaceutical compositions and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-111518101-A | Pyrrolopyrimidine derivatives and uses thereof | 湖北生物医药产业技术研究院有限公司 | 2020-08-11 | — | — | CN | disclosed |