SCHEMBL28898282

SCHEMBL28898282

CCC[C@@H](C(=O)Oc1ccccc1)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
KCNQ2 O43526 1/20 0.45
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
GPR88 Q9GZN0 3/20 0.43
GAA P10253 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ELANE P08246 1/20 0.41
PPARG P37231 2/20 0.41
PPARA Q07869 2/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7919741 1.00 ATM (0.53) ATML3MBTL1KCNQ2CYP1A2CYP3A4
SCHEMBL7913426 0.90 ATM (0.50) ATML3MBTL1CYP3A4GPR88TDP1
SCHEMBL10913216 0.89 ATM (0.49) ATML3MBTL1GPR88
SCHEMBL5146647 0.88 ATM (0.48) ATML3MBTL1
SCHEMBL10782796 0.88 ATM (0.48) ATML3MBTL1
SCHEMBL10783816 0.88 ATM (0.48) ATML3MBTL1
SCHEMBL10954043 0.88 ATM (0.48) ATML3MBTL1
SCHEMBL10953711 0.88 ATM (0.48) ATML3MBTL1
SCHEMBL10911342 0.88 ATM (0.48) ATML3MBTL1
SCHEMBL10779120 0.88 ATM (0.48) ATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111620781-B Alpha-alkyl phenylacetic acid compound with high optical activity and preparation method and application thereof 南京工业大学 2021-05-25 CN disclosed
CN-111620781-A Alpha-alkyl phenylacetic acid compound with high optical activity and preparation method and application thereof 南京工业大学 2020-09-04 CN disclosed