Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | EED | O75530 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20956996 | 0.91 | MEN1 (0.60) | MAPTSMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL15712181 | 0.83 | MAPT (0.45) | MAPTSMN1; SMN2EEDMEN1KMT2A | |
| SCHEMBL25184947 | 0.83 | ROCK1 (0.48) | MAPTSMN1; SMN2EEDMEN1KMT2A | |
| SCHEMBL30317408 | 0.83 | ROCK1 (0.48) | MAPTSMN1; SMN2EEDMEN1KMT2A | |
| SCHEMBL257551 | 0.82 | MAPT (0.47) | MAPTSMN1; SMN2EEDMEN1KMT2A | |
| SCHEMBL31038200 | 0.81 | MAPT (0.43) | MAPTSMN1; SMN2EEDMEN1KMT2A | |
| SCHEMBL28455024 | 0.81 | TP53 (0.53) | MAPTEEDMEN1KMT2ALMNA | |
| SCHEMBL7604954 | 0.80 | MAPT (0.45) | MAPTSMN1; SMN2EEDMEN1KMT2A | |
| SCHEMBL28400556 | 0.79 | ROCK1 (0.48) | MAPTSMN1; SMN2EEDMEN1KMT2A | |
| SCHEMBL29478502 | 0.79 | ROCK1 (0.51) | MAPTSMN1; SMN2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111732516-B | A kind ofNProcess for preparing (E) -aryl-substituted heterocyclic compounds | 南昌大学 | 2021-01-05 | — | — | CN | disclosed |
| CN-111732516-A | A kind ofNProcess for preparing (E) -aryl-substituted heterocyclic compounds | 南昌大学 | 2020-10-02 | — | — | CN | disclosed |