Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | KYNU | Q16719 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | KMO | O15229 | 3/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Kynurenine SCHEMBL288254 | 1.00 | KDM4E (0.64) | KDM4EHIF1ATDP1KYNUGAA | |
| Kynurenine SCHEMBL29349989 | 1.00 | KDM4E (0.64) | KDM4EHIF1ATDP1KYNUGAA | |
| L-Kynurenine SCHEMBL29396313 | 1.00 | KDM4E (0.64) | KDM4EHIF1ATDP1KYNUGAA | |
| L-Kynurenine SCHEMBL29415716 | 1.00 | KDM4E (0.64) | KDM4EHIF1ATDP1KYNUGAA | |
| L-Kynurenine SCHEMBL288989 | 1.00 | KDM4E (0.64) | KDM4EHIF1ATDP1KYNUGAA | |
| L-Kynurenine SCHEMBL13969610 | 1.00 | KDM4E (0.64) | KDM4EHIF1ATDP1KYNUGAA | |
| L-Kynurenine SCHEMBL20875 | 1.00 | KDM4E (0.64) | KDM4EHIF1ATDP1KYNUGAA | |
| Kynurenine SCHEMBL20874 | 1.00 | KDM4E (0.64) | KDM4EHIF1ATDP1KYNUGAA | |
| Kynurenine SCHEMBL2181581 | 1.00 | KDM4E (0.64) | KDM4EHIF1ATDP1KYNUGAA | |
| Kynurenine SCHEMBL2368792 | 0.98 | KDM4E (0.62) | KDM4EHIF1ATDP1KYNUGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024058984-A2 | METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING INSULIN-ASSOCIATED DISEASES | MarvelBiome, Inc. (US) | 2024-03-21 | — | — | WO | disclosed |
| US-20230086254-A1 | MEDICINAL COMPOSITION COMPRISING DENTAL PULP-DERIVED CELLS | JCR PHARMACEUTICALS CO., LTD. (JP) | 2023-03-23 | — | — | US | disclosed |
| WO-2018134329-A1 | METABOLIC BIOMARKER SET FOR ASSESSING OVARIAN CANCER | BIOCRATES LIFE SCIENCES AG (AT) | 2018-07-26 | — | — | WO | disclosed |
| EP-3191845-A1 | BIOMARKERS FOR ASSESSING BREAST CANCER | IDCGS Clínica de Diagnósticos Médicos Ltda (BR) | 2017-07-19 | — | — | EP | disclosed |
| EP-3126841-A1 | BIOMARKERS FOR ASSESSING HIV | IDCGS clinica de Diagnosticos Medicos (BR) | 2017-02-08 | — | — | EP | disclosed |
| WO-2016038157-A1 | BIOMARKERS FOR ASSESSING BREAST CANCER | IDCGS CLÍNICA DE DIAGNÓSTICOS MÉDICOS LTDA (BR) | 2016-03-17 | — | — | WO | disclosed |
| WO-2015150360-A1 | BIOMARKERS FOR ASSESSING HIV | IDCGS CLINICA DE DIAGNOSTICOS MEDICOS (BR) | 2015-10-08 | — | — | WO | disclosed |
| CN-104487457-A | Target tissue specific antigen binding molecules | CHUGAI PHARMACEUTICAL CO LTD | 2015-04-01 | — | — | CN | disclosed |
| WO-2012113834-A1 | METHOD AND USE OF METABOLITES FOR THE DIAGNOSIS OF INFLAMMATORY BRAIN INJURY IN PRETERM BORN INFANTS | BIOCRATES LIFE SCIENCES AG (AT) | 2012-08-30 | — | — | WO | disclosed |
| EP-2427773-A1 | METHOD OF DIAGNOSING ASPHYXIA | Keller, Matthias (DE) | 2012-03-14 | — | — | EP | disclosed |
| WO-2011062628-A1 | METHODS AND COMPOSITIONS FOR MODULATION OF T CELLS VIA THE KYNURENINE PATHWAY | NEW YORK UNIVERSITY (US) | 2011-05-26 | — | — | WO | disclosed |
| WO-2010128054-A1 | METHOD OF DIAGNOSING ASPHYXIA | BIOCRATES LIFE SCIENCES AG (AT) | 2010-11-11 | — | — | WO | disclosed |