Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CA7 | P43166 | 3/20 | 0.31 |
| ▸ | CA9 | Q16790 | 3/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28899064 | 0.92 | POLB (0.35) | POLBNPSR1TSHRSMN1; SMN2KDM4E | |
| SCHEMBL21612668 | 0.83 | TSHR (0.37) | POLBNPSR1TSHRALDH1A1KDM4E | |
| SCHEMBL10121177 | 0.79 | TSHR (0.46) | POLBNPSR1TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL1297587 | 0.79 | TSHR (0.46) | POLBNPSR1TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL2013269 | 0.78 | KDM4E (0.34) | TSHRSMN1; SMN2ALDH1A1KDM4EUSP2 | |
| SCHEMBL7858138 | 0.75 | BRD4 (0.44) | TSHRALDH1A1HSD17B10CYP2D6 | |
| SCHEMBL3048242 | 0.75 | BRD4 (0.44) | TSHRALDH1A1HSD17B10CYP2D6 | |
| SCHEMBL994649 | 0.75 | BRD4 (0.44) | TSHRALDH1A1HSD17B10CYP2D6 | |
| SCHEMBL2372196 | 0.75 | BRD4 (0.44) | TSHRALDH1A1HSD17B10CYP2D6 | |
| SCHEMBL15684230 | 0.75 | BRD4 (0.44) | TSHRALDH1A1HSD17B10CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232058-A | Synthesis method of gliclazide intermediate 1,2-cyclopentanedicarboxamide | 上海巽田科技股份有限公司 | 2022-10-25 | — | — | CN | disclosed |