Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.80 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.80 |
| ▸ | PKM | P14618 | 2/20 | 0.80 |
| ▸ | RAB9A | P51151 | 2/20 | 0.80 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.80 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.80 |
| ▸ | JAK2 | O60674 | 1/20 | 0.80 |
| ▸ | LMNA | P02545 | 1/20 | 0.80 |
| ▸ | GAA | P10253 | 1/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | JUN | P05412 | 1/20 | 0.62 |
| ▸ | MME | P08473 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29857286 | 0.89 | MAPT (1.00) | MAPTMAPK1ALDH1A1PKMRAB9A | |
| SCHEMBL10063287 | 0.89 | MAPT (1.00) | MAPTMAPK1ALDH1A1PKMRAB9A | |
| SCHEMBL28467807 | 0.85 | MAPT (0.81) | MAPTMAPK1ALDH1A1PKMRAB9A | |
| SCHEMBL28462169 | 0.84 | MAPT (0.90) | MAPTMAPK1ALDH1A1PKMRAB9A | |
| SCHEMBL28458033 | 0.83 | MAPT (0.88) | MAPTMAPK1ALDH1A1PKMRAB9A | |
| SCHEMBL29857561 | 0.79 | MAPT (0.80) | MAPTMAPK1ALDH1A1PKMRAB9A | |
| SCHEMBL28458916 | 0.78 | MAPT (0.76) | MAPTMAPK1ALDH1A1PKMRAB9A | |
| Cyclovalone SCHEMBL554418 | 0.78 | MEN1 (1.00) | MAPTMAPK1ALDH1A1PKMRAB9A | |
| Cyclovalone SCHEMBL554417 | 0.78 | MEN1 (1.00) | MAPTMAPK1ALDH1A1PKMRAB9A | |
| Cyclovalone SCHEMBL1151847 | 0.78 | MEN1 (1.00) | MAPTMAPK1ALDH1A1PKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107501219-B | Asymmetric curcumin compound and application thereof in preparation of anti-gastric cancer drugs | 温州医科大学 | 2020-09-25 | — | — | CN | disclosed |