Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.65 |
| ▸ | EGFR | P00533 | 9/20 | 0.52 |
| ▸ | KDR | P35968 | 8/20 | 0.52 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | KIF5B | P33176 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | CCR4 | P51679 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28899935 | 0.87 | SLC22A12 (0.65) | SLC22A12EGFRKDRHTTNTSR1 | |
| SCHEMBL28899774 | 0.83 | SLC22A12 (0.58) | SLC22A12HTTAPP | |
| SCHEMBL28899737 | 0.81 | SLC22A12 (0.48) | SLC22A12APP | |
| SCHEMBL28899925 | 0.79 | SLC22A12 (0.87) | SLC22A12 | |
| SCHEMBL28899756 | 0.79 | SLC22A12 (0.72) | SLC22A12KDRNTSR1 | |
| SCHEMBL28960094 | 0.79 | SLC22A12 (0.72) | SLC22A12EGFRKDRNTSR1RET | |
| SCHEMBL29259548 | 0.79 | SLC22A12 (0.78) | SLC22A12EGFRNTSR1 | |
| SCHEMBL28899857 | 0.78 | SLC22A12 (0.79) | SLC22A12 | |
| SCHEMBL15280232 | 0.75 | EGFR (0.76) | EGFRKDRHTTRET | |
| SCHEMBL30104177 | 0.75 | SLC22A12 (0.61) | SLC22A12KDRRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115417825-B | Five-membered or six-membered fused ring pyrimidine cyclopropyl naphthalene derivative and preparation method and application thereof | 山东大学 | 2024-06-28 | — | — | CN | disclosed |
| CN-115417825-A | Five-membered or six-membered fused ring pyrimidine cyclopropyl naphthalene derivative and preparation method and application thereof | 山东大学 | 2022-12-02 | — | — | CN | disclosed |