⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22989505 | 0.71 | — | — | |
| SCHEMBL28059573 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL27221546 | 0.69 | — | — | |
| SCHEMBL24807418 | 0.61 | — | — | |
| SCHEMBL24302581 | 0.60 | — | — | |
| SCHEMBL24585253 | 0.60 | — | — | |
| SCHEMBL22421413 | 0.59 | JAK2 (0.32) | — | |
| SCHEMBL20356358 | 0.59 | — | — | |
| SCHEMBL22989500 | 0.56 | — | — | |
| SCHEMBL15944144 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117903032-A | Preparation method of barytanib intermediate and method for preparing barytanib | 重庆博腾制药科技股份有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-115417876-B | Intermediate compound of barytinib | 山东新时代药业有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-115417876-A | Baritinib intermediate compound | 山东新时代药业有限公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-113480546-A | Preparation of Baricitinib and derivatives thereof | 江苏君若药业有限公司 | 2021-10-08 | — | — | CN | disclosed |
| CN-113480546-A | Preparation of Baricitinib and derivatives thereof | 江苏君若药业有限公司 | 2021-10-08 | — | — | CN | disclosed |