Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 10/20 | 1.00 |
| ▸ | ITGB1 | P05556 | 7/20 | 0.55 |
| ▸ | ITGA4 | P13612 | 7/20 | 0.55 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL289625 | 1.00 | CAPN1 (1.00) | CAPN1ITGB1ITGA4P2RX7 | |
| SCHEMBL288543 | 1.00 | CAPN1 (1.00) | CAPN1ITGB1ITGA4P2RX7 | |
| SCHEMBL289000 | 1.00 | CAPN1 (1.00) | CAPN1ITGB1ITGA4P2RX7 | |
| SCHEMBL288617 | 0.94 | CAPN1 (0.88) | CAPN1ITGB1ITGA4 | |
| SCHEMBL1612436 | 0.94 | CAPN1 (0.88) | CAPN1ITGB1ITGA4 | |
| SCHEMBL288910 | 0.94 | CAPN1 (0.88) | CAPN1ITGB1ITGA4 | |
| SCHEMBL289607 | 0.88 | CAPN1 (0.78) | CAPN1ITGB1ITGA4 | |
| SCHEMBL289988 | 0.88 | CAPN1 (0.78) | CAPN1ITGB1ITGA4P2RX7 | |
| SCHEMBL1612818 | 0.88 | CAPN1 (0.78) | CAPN1ITGB1ITGA4P2RX7 | |
| SCHEMBL288776 | 0.88 | CAPN1 (0.78) | CAPN1ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427429-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS | Abbott GmbH & Co. KG (DE) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128102-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS | ABBOTT GMBH & CO. KG (DE) | 2010-11-11 | — | — | WO | disclosed |