Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 1.00 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.55 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.55 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29597012 | 1.00 | TAAR1 (1.00) | TAAR1OPRL1OGFRL1DDB1CRBN | |
| SCHEMBL2636563 | 1.00 | TAAR1 (1.00) | TAAR1OPRL1OGFRL1DDB1CRBN | |
| SCHEMBL28901283 | 1.00 | TAAR1 (1.00) | TAAR1OPRL1OGFRL1DDB1CRBN | |
| SCHEMBL29596539 | 1.00 | TAAR1 (1.00) | TAAR1OPRL1OGFRL1DDB1CRBN | |
| SCHEMBL31512132 | 0.96 | TAAR1 (0.92) | TAAR1OPRL1OGFRL1DDB1CRBN | |
| Hydrochloric Acid SCHEMBL28152220 | 0.94 | TAAR1 (0.89) | TAAR1OPRL1OGFRL1DDB1CRBN | |
| Hydrochloric Acid SCHEMBL28334709 | 0.94 | TAAR1 (0.89) | TAAR1OPRL1OGFRL1DDB1CRBN | |
| SCHEMBL28138616 | 0.82 | TAAR1 (0.70) | TAAR1OPRL1OGFRL1CHRM1HRH1 | |
| SCHEMBL12470274 | 0.82 | TAAR1 (0.70) | TAAR1OPRL1OGFRL1CHRM1HRH1 | |
| SCHEMBL12470273 | 0.82 | TAAR1 (0.70) | TAAR1OPRL1OGFRL1CHRM1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114349781-A | Chiral pyrrolidine skeleton-containing aminophenoxy zinc complex and preparation method and application thereof | 华东理工大学 | 2022-04-15 | — | — | CN | disclosed |