SCHEMBL28901599

SCHEMBL28901599

CC(C)(C)OC(=O)C1C(=O)C(F)CNC1F

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.41
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5755941 0.70 MAPK1 (0.32) MAPK1
SCHEMBL17446122 0.68 MAPK1 (0.39) MAPK1GAA
SCHEMBL29119686 0.67
SCHEMBL29624397 0.64 MAPK1 (0.35) MAPK1
SCHEMBL2500543 0.64 CTSC (0.39) MAPK1
SCHEMBL11448952 0.64 CTSC (0.39) MAPK1
SCHEMBL29308167 0.64 CTSC (0.39) MAPK1
SCHEMBL14718807 0.62 MAPK1 (0.40) MAPK1GAA
SCHEMBL11448877 0.62 HRH3 (0.31) MAPK1
SCHEMBL16540393 0.62 MAPK1 (0.34) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115996719-A BRAF degradation agent C4医药公司 2023-04-21 CN disclosed
CN-115279370-A Compounds for targeted degradation of BRD9 C4医药公司 2022-11-01 CN disclosed