Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 11/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.42 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28902005 | 1.00 | FOLH1 (0.57) | FOLH1MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL19065187 | 0.92 | FOLH1 (0.56) | FOLH1MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL29728337 | 0.88 | FOLH1 (0.74) | FOLH1MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL23849705 | 0.88 | FOLH1 (0.56) | FOLH1MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL19065231 | 0.88 | FOLH1 (0.56) | FOLH1MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL22590164 | 0.86 | FOLH1 (0.61) | FOLH1MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL19065181 | 0.86 | FOLH1 (0.64) | FOLH1MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL31514312 | 0.86 | FOLH1 (0.51) | FOLH1PAX8TDP1PTPN1 | |
| SCHEMBL31514301 | 0.86 | FOLH1 (0.51) | FOLH1PAX8TDP1PTPN1 | |
| SCHEMBL19065267 | 0.86 | FOLH1 (0.60) | FOLH1MEN1ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114364405-A | Prostate Specific Membrane Antigen (PSMA) inhibitors as diagnostic agents and radionuclide therapeutics | 五一一制药股份有限公司 | 2022-04-15 | — | — | CN | disclosed |