SCHEMBL28902008

SCHEMBL28902008

CCOP(=O)(OCC)C(NC(=O)COC(N)=O)P(=O)(OCC)OCC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.39
GAA P10253 4/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
LMNA P02545 3/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
HTT P42858 1/20 0.34
THRB P10828 2/20 0.34
MAPT P10636 2/20 0.33
EED O75530 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
POLB P06746 1/20 0.32
MDM4 O15151 1/20 0.31
MDM2 Q00987 1/20 0.31
CAD P27708 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5276732 0.81 GAA (0.42) GAACYP3A4CYP2C9CYP2C19LMNA
SCHEMBL5274704 0.80 GAA (0.43) GAACYP3A4CYP2C9CYP2C19LMNA
SCHEMBL5273085 0.79 GAA (0.40) GAACYP3A4CYP2C9CYP2C19LMNA
SCHEMBL5276735 0.77 GAA (0.41) GAACYP3A4CYP2C9CYP2C19LMNA
SCHEMBL10910425 0.76 GAA (0.46) GAACYP3A4CYP2C9CYP2C19LMNA
SCHEMBL12232709 0.76 GAA (0.43) GAACYP3A4CYP2C9CYP2C19SMN1; SMN2
SCHEMBL1847963 0.76 GAA (0.43) GAACYP3A4CYP2C9CYP2C19LMNA
SCHEMBL5007400 0.76 GAA (0.43) GAACYP3A4CYP2C9CYP2C19LMNA
SCHEMBL5274699 0.76 CYP3A4 (0.42) GAACYP3A4CYP2C9CYP2C19LMNA
SCHEMBL5273087 0.74 CYP1A2 (0.41) GAACYP3A4CYP2C9CYP2C19POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114364405-B Prostate Specific Membrane Antigen (PSMA) inhibitors as diagnostic and radionuclide therapeutics 五一一制药股份有限公司 2024-07-16 CN disclosed
CN-114364405-A Prostate Specific Membrane Antigen (PSMA) inhibitors as diagnostic agents and radionuclide therapeutics 五一一制药股份有限公司 2022-04-15 CN disclosed