Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 5/20 | 0.58 |
| ▸ | MAOA | P21397 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 4/20 | 0.53 |
| ▸ | CA9 | Q16790 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | TTR | P02766 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30167104 | 1.00 | HSD17B3 (0.63) | HSD17B3MAOBMAOAKDM4EALDH1A1 | |
| SCHEMBL28902165 | 0.90 | MAOB (0.53) | HSD17B3MAOBMAOAKDM4EALDH1A1 | |
| SCHEMBL28874647 | 0.87 | MAOB (0.56) | HSD17B3MAOBMAOAKDM4EALDH1A1 | |
| SCHEMBL28902175 | 0.87 | KDM4E (0.57) | HSD17B3MAOBMAOAKDM4EALDH1A1 | |
| SCHEMBL28902193 | 0.87 | MAOB (0.52) | HSD17B3MAOBMAOAKDM4EALDH1A1 | |
| SCHEMBL28960194 | 0.84 | MAOB (0.49) | HSD17B3MAOBMAOAKDM4EALDH1A1 | |
| SCHEMBL28902174 | 0.84 | KDM4E (0.60) | MAOBMAOAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL28902198 | 0.84 | MAOB (0.76) | HSD17B3MAOBMAOAKDM4EALDH1A1 | |
| SCHEMBL30167103 | 0.83 | MAOB (0.79) | MAOBMAOACA12CA9CA1 | |
| SCHEMBL28902190 | 0.83 | MAOB (0.79) | MAOBMAOACA12CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115246805-B | Chromone-aniline alpha-glucosidase inhibitor and preparation method and application thereof | 贵州医科大学 | 2024-01-19 | — | — | CN | disclosed |
| CN-115246805-A | Chromone-aniline alpha-glucosidase inhibitor and preparation method and application thereof | 贵州医科大学 | 2022-10-28 | — | — | CN | disclosed |