Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.74 |
| ▸ | MAOA | P21397 | 1/20 | 0.74 |
| ▸ | CA12 | O43570 | 4/20 | 0.65 |
| ▸ | CA9 | Q16790 | 4/20 | 0.65 |
| ▸ | CA1 | P00915 | 3/20 | 0.65 |
| ▸ | CA2 | P00918 | 3/20 | 0.65 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | MARK4 | Q96L34 | 1/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30956090 | 0.91 | MAOB (0.59) | MAOBMAOACA12CA9CA1 | |
| SCHEMBL28902192 | 0.88 | MAOB (0.71) | MAOBMAOACA12CA9CA1 | |
| SCHEMBL28902170 | 0.85 | MAOB (1.00) | MAOBMAOACA12CA9CA1 | |
| SCHEMBL30167102 | 0.85 | MAOB (1.00) | MAOBMAOACA12CA9CA1 | |
| SCHEMBL30787472 | 0.85 | MAOB (0.60) | MAOBMAOACA12CA9CA1 | |
| SCHEMBL28902190 | 0.85 | MAOB (0.79) | MAOBMAOACA12CA9CA1 | |
| SCHEMBL30167103 | 0.85 | MAOB (0.79) | MAOBMAOACA12CA9CA1 | |
| SCHEMBL30787489 | 0.84 | MAOB (0.66) | MAOBMAOACA12CA9CA1 | |
| SCHEMBL28902198 | 0.83 | MAOB (0.76) | MAOBMAOACA12CA9CA1 | |
| SCHEMBL30787484 | 0.83 | MAOB (0.76) | MAOBMAOACA12CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117567419-A | Synthesis method of 3-amine methyl primary ketone derivative | 深圳职业技术大学 | 2024-02-20 | — | — | CN | disclosed |
| CN-115246805-B | Chromone-aniline alpha-glucosidase inhibitor and preparation method and application thereof | 贵州医科大学 | 2024-01-19 | — | — | CN | disclosed |
| CN-115246805-A | Chromone-aniline alpha-glucosidase inhibitor and preparation method and application thereof | 贵州医科大学 | 2022-10-28 | — | — | CN | disclosed |