Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 14/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30231217 | 1.00 | LCK (0.47) | LCKMAPTDYRK1ANPC1RAB9A | |
| SCHEMBL33525654 | 0.86 | LCK (0.49) | LCKMAPTNPC1RAB9A | |
| SCHEMBL25382677 | 0.84 | LCK (0.45) | LCKMAPTNPC1RAB9A | |
| SCHEMBL30231211 | 0.84 | LCK (0.45) | LCKMAPTNPC1RAB9A | |
| SCHEMBL30237087 | 0.83 | LCK (0.44) | LCKMAPTDYRK1A | |
| SCHEMBL28902830 | 0.83 | LCK (0.44) | LCKMAPTDYRK1A | |
| SCHEMBL21901580 | 0.81 | LCK (0.45) | LCKDYRK1A | |
| SCHEMBL21901426 | 0.81 | LCK (0.46) | LCK | |
| SCHEMBL30064634 | 0.81 | LCK (0.46) | LCK | |
| SCHEMBL30231276 | 0.80 | LCK (0.42) | LCKMAPTDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116390923-A | Heterocyclic derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-115403575-A | Heteroaromatic ring derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2022-11-29 | — | — | CN | disclosed |
| CN-115385912-A | Pyrazinopyrazinoquinolinone derivatives, preparation method and medical application thereof | 浙江海正药业股份有限公司 | 2022-11-25 | — | — | CN | disclosed |