Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | BLM | P54132 | 2/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | MPO | P05164 | 1/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | APAF1 | O14727 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | HTR2A | P28223 | 3/20 | 0.68 |
| ▸ | HTR1A | P08908 | 2/20 | 0.68 |
| ▸ | HTR2C | P28335 | 2/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.68 |
| ▸ | HTR7 | P34969 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dl-Tryptophan SCHEMBL289042 | 1.00 | KMT2A (1.00) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL475349 | 1.00 | KMT2A (1.00) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL7327 | 1.00 | KMT2A (1.00) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL475350 | 1.00 | KMT2A (1.00) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL4732053 | 1.00 | KMT2A (1.00) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL23141133 | 1.00 | KMT2A (1.00) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL1120026 | 1.00 | KMT2A (1.00) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL4732052 | 1.00 | KMT2A (1.00) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL19161120 | 1.00 | KMT2A (1.00) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL30343446 | 1.00 | KMT2A (1.00) | KMT2AKDM4EMAPTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924422-A | Tryptophan and tryptophan cross-chain interaction beta-hairpin antibacterial peptide as well as preparation method and application thereof | 东北农业大学 | 2024-04-26 | — | — | CN | claimed |
| WO-2024041535-A1 | NANO-COMPOSITION, PREPARATION METHOD THEREFOR, AND USE THEREOF | 赣州和美药业股份有限公司 | 2024-02-29 | — | — | WO | claimed |
| CN-117599013-A | Nanometer composition, preparation method and application thereof | 赣州和美药业股份有限公司 | 2024-02-27 | — | — | CN | claimed |
| CN-114099713-B | Molecular probe for in vivo detection of CDK4/6 kinase activity and application thereof | 厦门大学附属翔安医院 | 2023-09-01 | — | — | CN | claimed |
| CN-114099713-A | Molecular probe for in vivo detection of CDK4/6 kinase activity and application thereof | 厦门大学附属翔安医院 | 2022-03-01 | — | — | CN | claimed |
| CN-111182913-A | Methods and compositions for effective delivery through multiple biological barriers | 西奈医疗中心 | 2020-05-19 | — | — | CN | claimed |
| CN-102076221-B | The product for preparing the method for wrapped, the hot preserved aqueous drink comprising casein micelles and the peptide rich in tryptophan and thereby obtaining | 帝斯曼知识产权资产管理有限公司 | 2017-07-04 | — | — | CN | claimed |
| US-20160177329-A1 | METHOD OF INHIBITING SPROUTING IN PLANT TISSUES | ACADEMIA SINICA (TW) | 2016-06-23 | — | — | US | claimed |
| US-9230708-B2 | Self assembly of naphthalene diimide derivatives and process thereof | JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) | 2016-01-05 | — | — | US | claimed |
| US-20130302587-A1 | SELF ASSEMBLY OF NAPHTHALENE DIIMIDE DERIVATES AND PROCESS THEREOF | JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) | 2013-11-14 | — | — | US | claimed |
| EP-1589034-A2 | Rationally designed antibodies | ALEXION PHARMACEUTICALS, INC. (US) | 2005-10-26 | — | — | EP | claimed |
| EP-1370589-A2 | RATIONALLY DESIGNED ANTIBODIES | ALEXION PHARMACEUTICALS, INC. (US) | 2003-12-17 | — | — | EP | claimed |
| EP-1292609-A2 | PEPTIDES, COMPOSITIONS AND METHODS FOR THE TREATMENT OF BURKHOLDERIA CEPACIA | HERCULES INCORPORATED (US) | 2003-03-19 | — | — | EP | claimed |
| US-20030049683-A1 | Immunoglobulin for use in human therapeutics and diagnostics | ALEXION PHARMACEUTICAL, INC. | 2003-03-13 | — | — | US | claimed |
| WO-2002046238-A2 | RATIONALLY DESIGNED ANTIBODIES | ALEXION PHARMACEUTICALS, INC. (US) | 2002-06-13 | — | — | WO | claimed |
| US-20020051819-A1 | Peptides, compositions and methods for the treatment of burkholderia cepacia | HERCULES INCORPORATED | 2002-05-02 | — | — | US | claimed |
| WO-2001098364-A2 | PEPTIDES, COMPOSITIONS AND METHODS FOR THE TREATMENT OF BURKHOLDERIA CEPACIA | HERCULES INCORPORATED (US) | 2001-12-27 | — | — | WO | claimed |
| US-6232293-B1 | ADMINISTERING TRYPTOPHAN-TRYPTOPHAN, TRYPTOPHAN-TYROSINE, OR TYROSINE-TRYPTOPHAN DIPEPTIDE COUPLED TO PROTEIN OR PEPTIDE CARRIER AS ANTIINFLAMMATORY AGENT | ANDERSON BYRON E (US) | 2001-05-15 | — | — | US | claimed |
| US-5977076-A | CARRIER COUPLED TO DIPETIDE; ANTIINFLAMMATORY AGENTS; GRAFTING TISSUE | ANDERSON BYRON E (US) | 1999-11-02 | — | — | US | claimed |
| WO-1998046248-A1 | METHOD AND MATERIAL FOR INHIBITING COMPLEMENT | ANDERSON BYRON E (US) | 1998-10-22 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020051819-A1 | Peptides, compositions and methods for the treatment of burkholderia cepacia | NGLY1, VIP, CSTB | KMT2A 4667/4885KDM4E 4776/4885MAPT 4266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.