SCHEMBL28906190

SCHEMBL28906190

COC1COC2(C1)CN(C(=O)O)C2

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRM4 P08173 3/20 0.32
CHRM1 P11229 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30261978 1.00 CHRM4 (0.32) CHRM4CHRM1
SCHEMBL23150860 1.00 CHRM4 (0.32) CHRM4CHRM1
SCHEMBL21590471 0.80 USP2 (0.40) CHRM1
SCHEMBL21590472 0.80 USP2 (0.40) CHRM1
SCHEMBL21590710 0.80
SCHEMBL20722855 0.75 CNR2 (0.37)
SCHEMBL25256740 0.75 CNR2 (0.37)
SCHEMBL25304401 0.75 CNR2 (0.37)
SCHEMBL23150849 0.74 TSHR (0.48)
SCHEMBL23150880 0.74 TSHR (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115461337-A Novel triazolyl derivatives as GABA A alpha 5 PAM 豪夫迈·罗氏有限公司 2022-12-09 CN disclosed