Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29126180 | 0.89 | HSD17B10 (0.39) | RIPK1HSD17B10DPP4LMNAHPGD | |
| SCHEMBL28890612 | 0.87 | HPGD (0.37) | RIPK1HSD17B10LMNAHPGDCYP2C19 | |
| SCHEMBL29126207 | 0.85 | HPGD (0.40) | RIPK1HSD17B10LMNAHPGDCYP2C19 | |
| SCHEMBL23795131 | 0.77 | — | — | |
| SCHEMBL5164380 | 0.73 | HSD17B10 (0.40) | RIPK1HSD17B10LMNAHPGDBTK | |
| SCHEMBL23795126 | 0.72 | GAA (0.33) | RIPK1 | |
| SCHEMBL16793557 | 0.72 | — | — | |
| SCHEMBL6926899 | 0.72 | DPP4 (0.39) | RIPK1HSD17B10DPP4LMNAHPGD | |
| SCHEMBL21063648 | 0.71 | TP53 (0.33) | — | |
| SCHEMBL28195011 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116783199-A | Pyrazolo [1,5-A ] pyrazine derivatives as BTK inhibitors | 渤健马萨诸塞州股份有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-115461337-A | Novel triazolyl derivatives as GABA A alpha 5 PAM | 豪夫迈·罗氏有限公司 | 2022-12-09 | — | — | CN | disclosed |