SCHEMBL28906259

SCHEMBL28906259

CCCCCCCCN(CCC#N)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.43
JAK2 O60674 1/20 0.43
RAB9A P51151 1/20 0.43
PAX8 Q06710 1/20 0.43
USP2 O75604 1/20 0.42
HSD17B10 Q99714 1/20 0.42
KCNH2 Q12809 4/20 0.41
SLC16A3 O15427 1/20 0.40
SLC16A1 P53985 1/20 0.40
CNR2 P34972 2/20 0.39
ALDH1A1 P00352 1/20 0.39
ICMT O60725 1/20 0.38
ALB P02768 1/20 0.38
DRD3 P35462 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10491081 1.00 NPC1 (0.43) NPC1JAK2RAB9APAX8USP2
SCHEMBL10491085 1.00 NPC1 (0.43) NPC1JAK2RAB9APAX8USP2
SCHEMBL11800465 1.00 NPC1 (0.43) NPC1JAK2RAB9APAX8USP2
SCHEMBL9323694 0.93 HSD17B10 (0.44) USP2HSD17B10SLC16A3SLC16A1CNR2
SCHEMBL10773266 0.87 TSHR (0.43) USP2HSD17B10KCNH2ALDH1A1DRD3
SCHEMBL11702190 0.86 USP2 (0.46) USP2HSD17B10CNR2ALDH1A1DRD3
Nitrogen SCHEMBL5664480 0.86 NPC1 (0.50) NPC1JAK2RAB9APAX8KCNH2
SCHEMBL25227148 0.86 NPC1 (0.53) NPC1JAK2RAB9APAX8KCNH2
SCHEMBL25224466 0.86 NPC1 (0.53) NPC1JAK2RAB9APAX8KCNH2
SCHEMBL25223686 0.86 NPC1 (0.53) NPC1JAK2RAB9APAX8KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115279839-A Dye composition 纪和化学工业株式会社 2022-11-01 CN disclosed
CN-115244139-A Dye for dyeing with supercritical carbon dioxide 国立大学法人福井大学 2022-10-25 CN disclosed