Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 17/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5463505 | 0.84 | MAPK14 (0.54) | NAMPT | |
| SCHEMBL22922423 | 0.83 | NAMPT (0.58) | NAMPTMEN1KMT2A | |
| SCHEMBL15529281 | 0.83 | NAMPT (0.58) | NAMPTMEN1KMT2A | |
| SCHEMBL22859045 | 0.83 | NAMPT (0.58) | NAMPTMEN1KMT2A | |
| SCHEMBL22859047 | 0.83 | NAMPT (0.58) | NAMPTMEN1KMT2A | |
| SCHEMBL21590172 | 0.83 | NAMPT (0.63) | NAMPTGABRA5 | |
| SCHEMBL25211791 | 0.77 | NAMPT (0.57) | NAMPT | |
| SCHEMBL25255652 | 0.77 | NAMPT (0.57) | NAMPT | |
| SCHEMBL24230349 | 0.77 | NAMPT (0.57) | NAMPT | |
| SCHEMBL24230040 | 0.77 | NAMPT (0.52) | NAMPTGABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112243439-A | Pyrrolo [2,3-B ] pyridines or pyrrolo [2,3-B ] pyrazines as HPK1 inhibitors and uses thereof | 百济神州有限公司 | 2021-01-19 | — | — | CN | disclosed |