Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.83 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.83 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.83 |
| ▸ | RAF1 | P04049 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26708154 | 1.00 | KRAS (0.83) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL26708166 | 0.94 | KRAS (0.77) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL24857246 | 0.94 | KRAS (0.84) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL27212496 | 0.94 | KRAS (0.84) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL25800596 | 0.94 | KRAS (0.82) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL28960815 | 0.94 | KRAS (0.82) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL25136725 | 0.94 | KRAS (0.83) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL25136743 | 0.94 | KRAS (0.83) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL28906491 | 0.93 | KRAS (0.81) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL25602314 | 0.93 | KRAS (0.81) | KRASMAPK3MAPK1RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304623-A | Pyrimido-cyclic derivative and application thereof in medicine | 四川海思科制药有限公司 | 2022-11-08 | — | — | CN | disclosed |