SCHEMBL2890669

SCHEMBL2890669

COC(C)OC(=O)/C=C/C(=O)OC(C)OC

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 5/20 0.50
KEAP1 Q14145 1/20 0.46
NFE2L2 Q16236 1/20 0.46
CA12 O43570 1/20 0.34
AKR1B10 O60218 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
AKR1B1 P15121 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
CA14 Q9ULX7 1/20 0.34
TSHR P16473 1/20 0.32
KDM4E B2RXH2 1/20 0.31
GLA P06280 1/20 0.31
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31
RECQL P46063 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8416578 1.00 HCAR2 (0.50) HCAR2KEAP1NFE2L2CA12AKR1B10
SCHEMBL2899497 1.00 HCAR2 (0.50) HCAR2KEAP1NFE2L2CA12AKR1B10
SCHEMBL7538537 0.93 HCAR2 (0.61) HCAR2KEAP1NFE2L2CA12AKR1B10
SCHEMBL7538550 0.93 HCAR2 (0.61) HCAR2KEAP1NFE2L2CA12AKR1B10
SCHEMBL2890676 0.91 HCAR2 (0.65) HCAR2KEAP1NFE2L2CA12AKR1B10
SCHEMBL8416536 0.91 HCAR2 (0.43) HCAR2KEAP1NFE2L2CA12AKR1B10
SCHEMBL8416529 0.91 HCAR2 (0.43) HCAR2KEAP1NFE2L2CA12AKR1B10
SCHEMBL1069278 0.88 HCAR2 (0.40) HCAR2KEAP1NFE2L2CA12AKR1B10
SCHEMBL1069282 0.88 HCAR2 (0.40) HCAR2KEAP1NFE2L2CA12AKR1B10
SCHEMBL11286583 0.83 HCAR2 (0.36) HCAR2KEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2224279-B1 LIQUID CRYSTAL LIGHT CONTROL ELEMENT AND PROCESS FOR PRODUCING THE LIQUID CRYSTAL LIGHT CONTROL ELEMENT NIPPON SHEET GLASS CO LTD (JP) 2014-07-23 EP disclosed
US-8310626-B2 Liquid crystal light control device and method for producing the same comprising a step of emulsion polymerization of monomers of a liquid crystal resin composite NIPPON SHEET GLASS COMPANY, LIMITED (JP) 2012-11-13 US disclosed
US-20100302476-A1 LIQUID CRYSTAL LIGHT CONTROL DEVICE AND METHOD FOR PRODUCING THE SAME NIPPON SHEET GLASS COMPANY, LIMITED (JP) 2010-12-02 US disclosed
EP-2224279-A1 LIQUID CRYSTAL LIGHT CONTROL ELEMENT AND PROCESS FOR PRODUCING THE LIQUID CRYSTAL LIGHT CONTROL ELEMENT Nippon Sheet Glass Company Limited (JP) 2010-09-01 EP disclosed
EP-1331494-A1 COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL, AND PLASTIC LENS NOF CORPORATION (JP) 2003-07-30 EP disclosed
EP-0711813-B1 Antifouling coating composition HITACHI CHEMICAL CO LTD (JP) 2001-07-25 EP disclosed
US-5773508-A BIODEGRADABLE POLYMER OF ADDITION COPOLYMERS FOR PROTECTIVE COATINGS HITACHI CHEMICAL COMPANY, LTD. (JP) 1998-06-30 US disclosed
EP-0711813-A2 Coating varnish composition and antifouling coating composition Hitachi Chemical Co., Ltd. (JP) 1996-05-15 EP disclosed
EP-0297746-A2 Heat-curable silicone compositions comprising fumarate cure-control additive and use thereof DOW CORNING CORPORATION (US) 1989-01-04 EP disclosed
US-4774111-A PLATINUM CURABLE COATINGS, RELEASE AGENTS DOW CORNING CORPORATION (US) 1988-09-27 US disclosed