SCHEMBL2890674

SCHEMBL2890674

COCCOC(=O)/C=C/C(=O)OCCOC

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.56
HCAR2 Q8TDS4 8/20 0.52
KEAP1 Q14145 1/20 0.46
NFE2L2 Q16236 1/20 0.46
TSHR P16473 4/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
MAPT P10636 1/20 0.41
RAB9A P51151 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
ALDH1A1 P00352 2/20 0.41
TP53 P04637 2/20 0.41
HIF1A Q16665 2/20 0.41
HSD17B10 Q99714 1/20 0.41
MET P08581 1/20 0.38
HPGD P15428 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL403340 1.00 ATM (0.56) ATMHCAR2KEAP1NFE2L2TSHR
SCHEMBL5974049 1.00 ATM (0.56) ATMHCAR2KEAP1NFE2L2TSHR
SCHEMBL9719232 0.93 TSHR (0.52) ATMHCAR2KEAP1NFE2L2TSHR
SCHEMBL9719237 0.93 TSHR (0.52) ATMHCAR2KEAP1NFE2L2TSHR
SCHEMBL5182457 0.93 TSHR (0.52) ATMHCAR2KEAP1NFE2L2TSHR
SCHEMBL10713340 0.93 TSHR (0.52) ATMHCAR2KEAP1NFE2L2TSHR
SCHEMBL9719238 0.93 TSHR (0.52) ATMHCAR2KEAP1NFE2L2TSHR
SCHEMBL5180107 0.93 TSHR (0.52) ATMHCAR2KEAP1NFE2L2TSHR
SCHEMBL2890671 0.91 HCAR2 (0.67) ATMHCAR2KEAP1NFE2L2TSHR
SCHEMBL8416532 0.91 TSHR (0.50) ATMHCAR2KEAP1NFE2L2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4238577-A VULCANIZABLE ELASTOMERIC COPOLYMERS OF UNSATURATED ESTERS; RESISTANCE TO COLD AND OIL ABSORPTION AMERICAN CYANAMID COMPANY (US) 1980-12-09 US claimed
CN-112940258-A Reactive inhibitor and preparation method thereof, silicone rubber composition, silicone rubber and preparation method thereof 浙江清华柔性电子技术研究院 2021-06-11 CN disclosed
CN-107266314-B Method for synthesizing ethylene glycol methyl fumarate by ionic liquid catalysis 黄山学院 2020-04-10 CN disclosed
US-20170073600-A1 POLYMERS INFINEUM INT LTD (GB) 2017-03-16 US disclosed
EP-2224279-B1 LIQUID CRYSTAL LIGHT CONTROL ELEMENT AND PROCESS FOR PRODUCING THE LIQUID CRYSTAL LIGHT CONTROL ELEMENT NIPPON SHEET GLASS CO LTD (JP) 2014-07-23 EP disclosed
US-20140144070-A1 POLYMERS INFINEUM INTERNATIONAL LIMITED (GB) 2014-05-29 US disclosed
US-8710168-B2 Polymers INFINEUM INTERNATIONAL LIMITED (GB) 2014-04-29 US disclosed
US-8310626-B2 Liquid crystal light control device and method for producing the same comprising a step of emulsion polymerization of monomers of a liquid crystal resin composite NIPPON SHEET GLASS COMPANY, LIMITED (JP) 2012-11-13 US disclosed
US-20110146136-A1 Polymers INFINEUM INTERNATIONAL LIMITED (GB) 2011-06-23 US disclosed
US-20100302476-A1 LIQUID CRYSTAL LIGHT CONTROL DEVICE AND METHOD FOR PRODUCING THE SAME NIPPON SHEET GLASS COMPANY, LIMITED (JP) 2010-12-02 US disclosed
US-5795374-A SILYL ACRYLATE POLYMERS NOF CORPORATION (JP) 1998-08-18 US disclosed
US-5773508-A BIODEGRADABLE POLYMER OF ADDITION COPOLYMERS FOR PROTECTIVE COATINGS HITACHI CHEMICAL COMPANY, LTD. (JP) 1998-06-30 US disclosed
EP-0802243-A2 Coating composition NOF CORPORATION (JP) 1997-10-22 EP disclosed
EP-0711813-A2 Coating varnish composition and antifouling coating composition Hitachi Chemical Co., Ltd. (JP) 1996-05-15 EP disclosed
EP-0297746-A2 Heat-curable silicone compositions comprising fumarate cure-control additive and use thereof DOW CORNING CORPORATION (US) 1989-01-04 EP disclosed
US-4774111-A PLATINUM CURABLE COATINGS, RELEASE AGENTS DOW CORNING CORPORATION (US) 1988-09-27 US disclosed
US-4255547-A A VULCANIZABLE COPOLYMER COMPRISING AN ACRYLIC ACID ESTER, BIS(2-METHOXYETHYL FUMARATE OR MALEATE, AND A HALO- OR EPOXY-CONTAINING UNSATURATED MONOMER; COLD RESISTANCE AMERICAN CYANAMID COMPANY (US) 1981-03-10 US disclosed
US-4255547-A A VULCANIZABLE COPOLYMER COMPRISING AN ACRYLIC ACID ESTER, BIS(2-METHOXYETHYL FUMARATE OR MALEATE, AND A HALO- OR EPOXY-CONTAINING UNSATURATED MONOMER; COLD RESISTANCE AMERICAN CYANAMID COMPANY (US) 1981-03-10 US disclosed
US-4238577-A VULCANIZABLE ELASTOMERIC COPOLYMERS OF UNSATURATED ESTERS; RESISTANCE TO COLD AND OIL ABSORPTION AMERICAN CYANAMID COMPANY (US) 1980-12-09 US disclosed
US-4238577-A VULCANIZABLE ELASTOMERIC COPOLYMERS OF UNSATURATED ESTERS; RESISTANCE TO COLD AND OIL ABSORPTION AMERICAN CYANAMID COMPANY (US) 1980-12-09 US disclosed