Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30128086 | 1.00 | KRAS (0.63) | KRAS | |
| SCHEMBL28907105 | 1.00 | KRAS (0.63) | KRAS | |
| SCHEMBL21542651 | 0.93 | KRAS (0.65) | KRAS | |
| SCHEMBL31745242 | 0.93 | KRAS (0.65) | KRAS | |
| SCHEMBL21542653 | 0.93 | KRAS (0.65) | KRAS | |
| SCHEMBL28382317 | 0.92 | KRAS (0.60) | KRAS | |
| SCHEMBL26330108 | 0.92 | KRAS (0.60) | KRAS | |
| SCHEMBL29551388 | 0.92 | KRAS (0.60) | KRAS | |
| SCHEMBL21542965 | 0.90 | KRAS (0.61) | KRAS | |
| SCHEMBL21542968 | 0.90 | KRAS (0.61) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112159405-B | Pyridopyrimidinone compounds and application thereof | 广州必贝特医药技术有限公司 | 2021-09-14 | — | — | CN | disclosed |
| CN-112159405-A | Pyridopyrimidinone compounds and application thereof | 广州必贝特医药技术有限公司 | 2021-01-01 | — | — | CN | disclosed |