Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.53 |
| ▸ | BRD4 | O60885 | 5/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.50 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.50 |
| ▸ | TNF | P01375 | 1/20 | 0.50 |
| ▸ | IL1B | P01584 | 1/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.50 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.49 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.48 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24778362 | 0.94 | CRBN (0.57) | CRBNBRD4HDAC3HDAC1IKZF1 | |
| Hydrochloric Acid SCHEMBL31065058 | 0.94 | CRBN (0.56) | CRBNBRD4HDAC3HDAC1IKZF1 | |
| Hydrochloric Acid SCHEMBL23037363 | 0.94 | CRBN (0.56) | CRBNBRD4HDAC3HDAC1IKZF1 | |
| SCHEMBL20913681 | 0.93 | CRBN (0.55) | CRBNBRD4HDAC3HDAC1IKZF1 | |
| SCHEMBL23772826 | 0.93 | CRBN (0.55) | CRBNBRD4HDAC3HDAC1IKZF1 | |
| SCHEMBL17821424 | 0.93 | CRBN (0.55) | CRBNBRD4HDAC3HDAC1IKZF1 | |
| Trifluoroacetic Acid SCHEMBL30045679 | 0.88 | CRBN (0.55) | CRBNBRD4HDAC3HDAC1IKZF1 | |
| SCHEMBL25031475 | 0.87 | CRBN (0.52) | CRBNBRD4HDAC3HDAC1IKZF1 | |
| Trifluoroacetic Acid SCHEMBL17873758 | 0.87 | CRBN (0.54) | CRBNBRD4HDAC3HDAC1IKZF1 | |
| Trifluoroacetic Acid SCHEMBL29922473 | 0.87 | CRBN (0.54) | CRBNBRD4HDAC3HDAC1IKZF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433257-A | Imidazopyridazine bifunctional PROTAC molecular compound and preparation and application thereof | 广西大学 | 2022-12-06 | — | — | CN | disclosed |