Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6383804 | 0.94 | MAPT (0.58) | MAPTALDH1A1KDM4EPOLBAKR1C1 | |
| SCHEMBL6383807 | 0.94 | MAPT (0.58) | MAPTALDH1A1KDM4EPOLBAKR1C1 | |
| SCHEMBL4007167 | 0.90 | AKR1C1 (0.63) | MAPTALDH1A1KDM4EPOLBAKR1C1 | |
| SCHEMBL11743667 | 0.90 | AKR1C1 (0.63) | MAPTALDH1A1KDM4EPOLBAKR1C1 | |
| SCHEMBL4007174 | 0.90 | AKR1C1 (0.63) | MAPTALDH1A1KDM4EPOLBAKR1C1 | |
| SCHEMBL1981785 | 0.81 | AKR1C1 (0.78) | MAPTALDH1A1KDM4EPOLBAKR1C1 | |
| SCHEMBL14591173 | 0.81 | AKR1C1 (0.78) | MAPTALDH1A1KDM4EPOLBAKR1C1 | |
| SCHEMBL28896121 | 0.81 | CYP1B1 (0.52) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL7240015 | 0.81 | CYP1B1 (0.52) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL4008619 | 0.81 | MEN1 (0.55) | MAPTALDH1A1KDM4EPOLBAKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112209896-B | Thiazolidinedione derivatives and pharmaceutical compositions containing the same | 苏州泽璟生物制药股份有限公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-112209896-A | Thiazolidinedione derivatives and pharmaceutical compositions containing the same | 苏州泽璟生物制药股份有限公司 | 2021-01-12 | — | — | CN | disclosed |