Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1938703 | 0.88 | — | — | |
| SCHEMBL3079235 | 0.74 | — | — | |
| Propionic Acid SCHEMBL27803778 | 0.70 | FFAR3 (0.53) | FFAR3TDP1ALDH1A1 | |
| Propionic Acid SCHEMBL28317032 | 0.69 | FFAR3 (0.71) | FFAR3TDP1ALDH1A1 | |
| SCHEMBL3070496 | 0.69 | — | — | |
| SCHEMBL6736948 | 0.68 | — | — | |
| Bicarbonate SCHEMBL11505805 | 0.67 | — | — | |
| Bicarbonate SCHEMBL6620515 | 0.67 | — | — | |
| SCHEMBL8537408 | 0.67 | — | — | |
| SCHEMBL10384574 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108201773-B | Method for absorbing volatile organic compounds in gas by using hydrophilic switchable reversible solvent | 昆明理工大学 | 2021-03-02 | — | — | CN | disclosed |