SCHEMBL2890748

SCHEMBL2890748

N[C@H](C(=O)O)C(CO)Cc1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 4/20 0.62
SLC1A2 P43004 4/20 0.62
SLC1A1 P43005 4/20 0.62
ALPI P09923 1/20 0.58
PKM P14618 1/20 0.58
PTGS1 P23219 1/20 0.58
XIAP P98170 1/20 0.58
SLC7A5 Q01650 1/20 0.58
CYP1A2 P05177 2/20 0.52
SRR Q9GZT4 2/20 0.49
MEN1 O00255 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
KMT2A Q03164 1/20 0.49
EPHX1 P07099 2/20 0.47
SLC15A1 P46059 1/20 0.46
LAP3 P28838 3/20 0.46
CPA1 P15085 2/20 0.46
CPA3 P15088 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2890750 1.00 SLC1A3 (0.62) SLC1A3SLC1A2SLC1A1ALPIPKM
SCHEMBL27348648 0.90 SLC1A3 (0.69) SLC1A3SLC1A2SLC1A1ALPIPKM
Diethylamine SCHEMBL29024453 0.89 SLC1A3 (0.51) SLC1A3SLC1A2SLC1A1ALPIPKM
Diethylamine SCHEMBL29024452 0.89 SLC1A3 (0.51) SLC1A3SLC1A2SLC1A1ALPIPKM
SCHEMBL14420246 0.84 SLC1A3 (0.61) SLC1A3SLC1A2SLC1A1ALPIPKM
SCHEMBL14420344 0.84 SLC1A3 (0.61) SLC1A3SLC1A2SLC1A1ALPIPKM
SCHEMBL4367490 0.84 SLC1A3 (0.61) SLC1A3SLC1A2SLC1A1ALPIPKM
SCHEMBL1101111 0.84 SLC1A3 (0.61) SLC1A3SLC1A2SLC1A1ALPIPKM
SCHEMBL27644705 0.84 SLC1A3 (0.61) SLC1A3SLC1A2SLC1A1ALPIPKM
SCHEMBL27665297 0.81 SLC1A3 (0.57) SLC1A3SLC1A2SLC1A1ALPIPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7807678-B2 Peptidomimetics of biologically active metallopeptides PALATIN TECHNOLOGIES, INC. (US) 2010-10-05 US disclosed
US-7718802-B2 Agonist or antgonist and binders and inversion of agonist; use in the treatment of metabolic, immune, infection-related and melanocortin receptor mediated disorders PALATIN TECHNOLOGIES, INC. (US) 2010-05-18 US disclosed
US-7655658-B2 Use of in the treatment of melanocortin receptor-associated disorders such as in treatment of anorexia, as a weight gain aid, for treatment of obesity PALATIN TECHNOLOGIES, INC. (US) 2010-02-02 US disclosed
WO-2009144432-A1 MC4-R AGONISTS FOR THE TREATMENT OF OBESITY PALATIN TECHNOLOGIES, INC. (US) 2009-12-03 WO disclosed
US-7550602-B1 Small molecule compositions for sexual dysfunction PALATIN TECHNOLOGIES, INC. (US) 2009-06-23 US disclosed
US-7456184-B2 Melanocortin receptor-specific compounds PALATIN TECHNOLOGIES INC. (US) 2008-11-25 US disclosed
EP-1622618-A4 MELANOCORTIN RECEPTOR-SPECIFIC COMPOUNDS PALATIN TECHNOLOGIES INC (US) 2008-08-27 EP disclosed
US-7326707-B2 Bicyclic melanocortin-specific compounds PALATIN TECHNOLOGIES INCORPORATED (US) 2008-02-05 US disclosed
EP-1425029-A4 PEPTIDOMIMETICS OF BIOLOGICALLY ACTIVE METALLOPEPTIDES PALATIN TECHNOLOGIES INC (US) 2006-06-07 EP disclosed
EP-1622618-A1 MELANOCORTIN RECEPTOR-SPECIFIC COMPOUNDS Palatin Technologies, Inc. (US) 2006-02-08 EP disclosed
WO-2005102340-A1 PIPERAZINE MELANOCORTIN-SPECIFIC COMPOUNDS PALATIN TECHNOLOGIES, INC. (US) 2005-11-03 WO disclosed
WO-2005079574-A1 BICYCLIC MELANOCORIN-SPECIFIC COMPOUNDS PALATIN TECHNOLOGIES, INC. (US) 2005-09-01 WO disclosed
US-20050176728-A1 Agonist or antgonist and binders and inversion of agonist; use in the treatment of metabolic, immune, infection-related and melanocortin receptor mediated disorders PALATIN TECHNOLOGIES, INC. (US) 2005-08-11 US disclosed
WO-2004098602-A1 MELANOCORTIN RECEPTOR-SPECIFIC COMPOUNDS PALATIN TECHNOLOGIES, INC. (US) 2004-11-18 WO disclosed
EP-1425029-A1 PEPTIDOMIMETICS OF BIOLOGICALLY ACTIVE METALLOPEPTIDES Palatin Technologies, Inc. (US) 2004-06-09 EP disclosed
WO-2003013571-A1 PEPTIDOMIMETICS OF BIOLOGICALLY ACTIVE METALLOPEPTIDES PALATIN TECHNOLOGIES, INC. (US) 2003-02-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050176728-A1 Agonist or antgonist and binders and inversion of agonist; use in the treatment of metabolic, immune, infection-related and melanocortin receptor mediated disorders MC3R, MC4R, MC1R SLC1A3 919/4885SLC1A2 614/4885SLC1A1 786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.