Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 10/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8258775 | 0.92 | KCNH2 (0.41) | KCNH2SCN3AALDH1A1TDP1MAPT | |
| SCHEMBL28519301 | 0.91 | KCNH2 (0.38) | KCNH2SCN3AALDH1A1TDP1MAPT | |
| SCHEMBL2347960 | 0.88 | KCNH2 (0.38) | KCNH2SCN3AALDH1A1TDP1MAPT | |
| SCHEMBL24220439 | 0.87 | KCNH2 (0.49) | KCNH2SCN3AALDH1A1TDP1MAPT | |
| SCHEMBL20835748 | 0.87 | KCNH2 (0.49) | KCNH2SCN3AALDH1A1TDP1MAPT | |
| SCHEMBL3585032 | 0.86 | KCNH2 (0.56) | KCNH2SCN3AALDH1A1TDP1SCN1A | |
| SCHEMBL4637528 | 0.86 | KCNH2 (0.56) | KCNH2SCN3AALDH1A1TDP1SCN1A | |
| SCHEMBL2350627 | 0.86 | KCNH2 (0.56) | KCNH2SCN3AALDH1A1TDP1SCN1A | |
| SCHEMBL3585037 | 0.86 | KCNH2 (0.56) | KCNH2SCN3AALDH1A1TDP1SCN1A | |
| SCHEMBL4637526 | 0.86 | KCNH2 (0.56) | KCNH2SCN3AALDH1A1TDP1SCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476639-B | Pyrrolidine derivatives | 橘生药品工业股份有限公司 | 2021-02-26 | — | — | CN | disclosed |