Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 1/20 | 0.60 |
| ▸ | BTK | Q06187 | 1/20 | 0.60 |
| ▸ | PPARA | Q07869 | 3/20 | 0.58 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | CTSS | P25774 | 4/20 | 0.53 |
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2890895 | 1.00 | JAK3 (0.60) | JAK3BTKPPARAPPARGCTSS | |
| SCHEMBL2897805 | 0.89 | PPARA (0.67) | JAK3BTKPPARAPPARGCTSS | |
| SCHEMBL30836085 | 0.89 | PPARA (0.67) | JAK3BTKPPARAPPARGCTSS | |
| SCHEMBL2897802 | 0.89 | PPARA (0.67) | JAK3BTKPPARAPPARGCTSS | |
| SCHEMBL6462882 | 0.86 | JAK3 (0.64) | JAK3BTKPPARAPPARGCTSS | |
| SCHEMBL3763894 | 0.86 | JAK3 (0.64) | JAK3BTKPPARAPPARGCTSS | |
| SCHEMBL3720453 | 0.86 | JAK3 (0.64) | JAK3BTKPPARAPPARGCTSS | |
| SCHEMBL22344639 | 0.86 | JAK3 (0.43) | JAK3BTKPPARACTSB | |
| SCHEMBL18989376 | 0.86 | JAK3 (0.43) | JAK3BTKPPARACTSB | |
| SCHEMBL3348663 | 0.85 | PPARA (0.64) | PPARAPPARGCTSSCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820680-B2 | HIV integrase inhibitors | MERCK & CO., INC. (US) | 2010-10-26 | — | — | US | disclosed |
| US-20080009490-A1 | Hiv Integrase Inhibitors | MERCK SHARP & DOHME CORP. | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009490-A1 | Hiv Integrase Inhibitors | TYMS, UNG, TYMP | JAK3 1592/4885BTK 239/4885PPARA 4759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.