Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 11/20 | 0.58 |
| ▸ | CCND1 | P24385 | 11/20 | 0.58 |
| ▸ | CCND2 | P30279 | 11/20 | 0.58 |
| ▸ | CCND3 | P30281 | 11/20 | 0.58 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.46 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.46 |
| ▸ | CDK1 | P06493 | 3/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.46 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.46 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.46 |
| ▸ | CDK2 | P24941 | 3/20 | 0.46 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.46 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 4/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28909368 | 1.00 | CDK4 (0.58) | CDK4CCND1CCND2CCND3CCNB2 | |
| SCHEMBL23141897 | 0.92 | CDK4 (0.55) | CDK4CCND1CCND2CCND3CCNB2 | |
| SCHEMBL23141899 | 0.92 | CDK4 (0.55) | CDK4CCND1CCND2CCND3CCNB2 | |
| SCHEMBL29831367 | 0.89 | CDK4 (0.61) | CDK4CCND1CCND2CCND3CCNB2 | |
| SCHEMBL23141769 | 0.89 | CDK4 (0.61) | CDK4CCND1CCND2CCND3CCNB2 | |
| SCHEMBL23141766 | 0.89 | CDK4 (0.61) | CDK4CCND1CCND2CCND3CCNB2 | |
| SCHEMBL30718272 | 0.88 | CDK4 (0.48) | CDK4CCND1CCND2CCND3CCNB2 | |
| SCHEMBL23141683 | 0.88 | CDK4 (0.48) | CDK4CCND1CCND2CCND3CCNB2 | |
| SCHEMBL23141685 | 0.88 | CDK4 (0.48) | CDK4CCND1CCND2CCND3CCNB2 | |
| SCHEMBL28537531 | 0.88 | CDK4 (0.69) | CDK4CCND1CCND2CCND3CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112469719-A | Heterocondensed pyridone compounds and their use as IDH inhibitors | 内尔维亚诺医疗科学公司 | 2021-03-09 | — | — | CN | claimed |
| CN-112469719-A | Heterocondensed pyridone compounds and their use as IDH inhibitors | 内尔维亚诺医疗科学公司 | 2021-03-09 | — | — | CN | disclosed |